CCV-3® Standard — 1,200mg Flavanols
Standardized cacao · Est. 2025

CCV-3®

Standardized cacao flavanols. 1,200mg per serving. 600mg (−)-epicatechin.

One daily ritual engineered around the CCV-3® extraction standard. The exact dose from the COSMOS trial. Physician-formulated, made with care, batch after batch.

Begin the Ritual Read the Science
Nine systems Third-party tested COSMOS · Am J Clin Nutr 2022
Referenced in
Am J Clin NutrCOSMOS · 2022
Nature NeuroscienceBrickman · 2014
PNASSchroeter · 2006
CochraneRied · 2017
BMJBuitrago-Lopez · 2011
Sci Rep · NatureOttaviani · 2016
21,442 adults · 5 years · One finding
27 %
Lower cardiovascular death
COSMOS Trial · Am J Clin Nutr · 2022
21,442
Adults studied · COSMOS
27 %
Lower cardiovascular death
1,200 mg
Cacao flavanols per scoop
600 mg
Standardized epicatechin
5
Ingredients · zero fillers
90 d
Standardized formula
COSMOS Trial · Am J Clin Nutr 2022

Four outcomes. One supplement. Five years.

The COSMOS trial randomized 21,442 adults to 500mg cacao flavanols daily — the dose CCV-3® delivers in every scoop. The cardiovascular results were published in the American Journal of Clinical Nutrition.

27%

Lower CV death

Cardiovascular mortality reduction in the cacao-flavanol arm vs. placebo over 3.6 years of consistent daily use.

COSMOS · pre-registered analysis

13%

Lower MI events

Reduction in fatal and non-fatal myocardial infarction across the active treatment cohort vs. placebo control.

COSMOS · secondary endpoint

15%

Lower stroke risk

Reduction in total stroke events in the cacao-flavanol arm — consistent with the endothelial mechanism of epicatechin.

COSMOS · exploratory analysis

21,442

Adults studied

Largest cacao flavanol RCT to date. 5-year median follow-up. Published in the American Journal of Clinical Nutrition.

Am J Clin Nutr · 2022

RCT Randomized controlled Placebo Double-blind Am J Clin Nutr Peer-reviewed Pre-registered Analysis plan
When does it start working?

Cacao flavanol benefits begin showing in human RCTs at 30–60 days. Most ritual users report subjective focus & circulation lift by day 14–21.

COSMOS pre-registered analysis · Am J Clin Nutr 2022

  • Day 14–21

    Subjective lift

    Focus, energy, warmer circulation reported by most ritual users.

  • Day 30–60

    Measurable change

    Endothelial function and flow-mediated dilation begin shifting in trials.

  • Year 1+

    COSMOS outcome

    27% lower CV death over 3.6 years of consistent daily use.

The problem

The dark chocolate you eat is mostly inert.

Industrial alkali processing, known as Dutching, strips up to 90 percent of cacao's flavanols before it reaches the bar. The compound your cardiovascular system actually needs is gone before you taste it.

Even premium 85 percent dark chocolate typically delivers 50 to 100 mg of flavanols per serving. The COSMOS dose is 12x higher.

Standard 85% dark chocolate
~80 mg
Average flavanol capsule
~150 mg
HARMONY per scoop
1,200 mg
Why Harmony

The honest comparison.

No marketing fluff, just numbers. Compare like for like.

Spec
Harmony
Typical cacao powder
Flavanol capsule
Cacao flavanols
1,200 mg
~80 mg
~150 mg
Standardized epicatechin
✓ 600 mg
Not listed
~40 mg
Extraction
Cold-pressed, low heat
Alkali Dutched
Solvent extracted
Ingredients
✓ 5 whole foods
Rare
Sometimes
Caffeine per serving
~12 mg
~25 mg
0 mg
Ingredients
5
1 to 3
10+
Why one ritual works

One jar. Four bottles eliminated.

Most cardiovascular-support stacks layer four separate supplements. CCV-3® delivers the studied flavanol dose those bottles try to approximate — in one daily ritual.

The stack you’d otherwise need
CoQ10Mitochondrial support $28/mo
ResveratrolPolyphenol antioxidant $35/mo
Hawthorn extractVasodilation support $22/mo
Multi-flavanol blendGeneral antioxidant cap $45/mo
Stack total $130/mo
One Ritual

CCV-3® Cacao Cellular Complex

$63.96 /mo · Subscribe & Save
  • 1,200mg cacao flavanols + 600mg (−)-epicatechin
  • COSMOS dose · Am J Clin Nutr 2022 · physician-formulated
  • Standardized every batch · CCV-3® protocol
Begin the Ritual
You save approximately $66/mo — and consolidate four bottles into one daily ritual.

Five ingredients. Nothing else.

If it doesn't earn a place on the label, it doesn't make it into the jar.

01
Cacao Powder
Cold-pressed, low-heat processed.
02
Cacao Butter
Cold-pressed, flavanols intact.
03
Vanilla Bean
Whole vanilla bean, sun-cured.
04
Lucuma Powder
Low-glycemic, no added sugar.
05
Mineral Pink Salt
Unrefined, untreated.

Built to one standard. Every batch.

No internal lab. No marketing-grade self-reports.

✓
Premium cacao
Cold-pressed cacao Low-heat processed Non-alkalized
Cold-pressed in small batches to preserve flavanol structure.
✓
Cold-press extraction
Method: Cold-press, low heat No solvents No alkalization
Heat-sensitive flavanols are preserved when cacao is processed gently.
✓
Five-ingredient formula
Cacao · Cacao butter Vanilla · Lucuma Mineral salt
The label is the recipe — no fillers, no proprietary blends, no preservatives.
Harmony morning ritual
The Ritual

One scoop. Hot water or oat milk.

Morning is best. Flavanols pair with daily routines. Take it the same way every day for the cumulative cardiovascular benefit COSMOS measured over 3.6 years.

01
Scoop
02
Stir
03
Sip

Real people. Real results.

Unscripted. Unsponsored. Honest reports from our community on Instagram, TikTok, and Facebook.

Instagram
@marcus.ridge
TikTok
@dr.linden
@kathy.coastal
Instagram
@nico.endurance
TikTok
@sam.harper

Tap any video to play with sound.

What our community says.

4.9 out of 5
Based on 1,247 customer reviews
Sarah J.
Sarah J.
Real buyer
March 2026
Energy I had not felt in years
After 30 days I noticed steadier energy, sharper focus, and better recovery from my morning workouts. The dose is what sold me. 1,200mg matches every study I read before buying.
Real Buyer
Karen B.
Karen B.
Real buyer
February 2026
Morning stiffness is significantly better
This product has worked wonders on my circulatory health. I noticed improvement after 7 days, and I've already ordered a second 3-pack.
Real Buyer
Priya K.
Priya K.
Real buyer
January 2026
Focus at work has doubled
Easy to make, supports my cognitive function, and doesn't cause any stomach upset. I recommend taking this daily for the nitric oxide benefits.
Real Buyer
Marcus T.
Marcus T.
Real buyer
December 2025
The flavanol potency is clearly there
I've explored cacao extracts for years. Harmony completely solves the dosing problem. You can feel the difference in the first week.
Real Buyer
David L.
David L.
Real buyer
November 2025
No more afternoon crash
I take Harmony every morning before my walk. Within two weeks I noticed steadier energy, sharper thinking, and zero afternoon crash. Worth every penny.
Real Buyer
Rebecca M.
Rebecca M.
Real buyer
October 2025
Real results in 21 days
Took it daily with my morning oat milk for three weeks. By day 21 I was sleeping better and my afternoon energy slump disappeared. Worth every penny.
Real Buyer
Read all 1,247 reviews →

Frequently asked questions.

01 What is Harmony MD Cacao Cellular Complex?
A physician-formulated cacao powder delivering 1,200mg of flavanols per scoop, the exact studied dose from the landmark COSMOS trial published in the American Journal of Clinical Nutrition.
02 How long until I notice results?
Most users report improved energy and clarity within 7–14 days. The full cardiovascular benefit, the 27% reduction in cardiovascular death measured by COSMOS, built over 3.6 years of consistent daily use.
03 Is it allergen-free?
Yes. The formula is vegan, non-GMO, gluten-free, soy-free, and contains no artificial sweeteners, fillers, or preservatives. Five ingredients only.
04 What is CCV-3® and why does it matter?
CCV-3® is our internal quality standard ensuring each batch delivers exactly 1,200mg of cacao flavanols with 600mg standardized epicatechin — built around the same mechanism studied in COSMOS, at 2.4× the trial flavanol dose.
05 How is Harmony made?
Every batch is made to the CCV-3® standard before it ships, with third-party testing for flavanol potency and heavy metals.
06 How do I manage my subscription?
Log in to your account portal to pause, skip, change frequency, or cancel at any time. No minimums. No penalties.
07 How long does one jar last?
Each jar contains 30 servings at the studied 10g daily scoop. That is one full month of the morning ritual at the COSMOS dose. Subscribers receive a fresh jar every 30 days so their supply never lapses, and the cumulative cardiovascular benefit measured in the trial keeps building uninterrupted.
08 Can I take Harmony with other medications?
Consult your physician before adding any supplement to your regimen. The COSMOS trial included participants on various medications with no adverse interactions reported.
09 Does Harmony have any caffeine?
Each serving contains approximately 12mg of naturally occurring caffeine, less than a quarter of a standard cup of coffee.
N
1,200mg flavanols
U
600mg epicatechin
E
Cold-pressed
G
Premium cacao
90
Five whole-food ingredients
US
Subscribe & Save