1,200 mg of cacao flavanols. 600 mg of standardized epicatechin. The exact dose linked to a 27% reduction in cardiovascular death across 21,442 adults studied in the COSMOS trial.
Begin the heart ritualCOSMOS · Am J Clin Nutr 2022 · Brigham & Women's Hospital · Harvard Medical School
Standardized cacao flavanol complex for the long arc of heart health. The 1,200 mg dose studied in the COSMOS trial across 21,442 adults for 3.6 years.
One scoop. 8 oz hot water or oat milk. Once a day.
The cardiovascular benefit COSMOS measured was cumulative over 3.6 years. The dose is non-negotiable. The cultivars carry it. Every batch is standardized to the CCV-3® dose before it ships.
Other ingredients: none. No fillers. No proprietary blends. No preservatives.
One scoop. Eight ounces of warm oat milk or hot water. Morning, with breakfast.
Best for cardiovascular outcomes: consistent daily intake. The COSMOS trial measured 27% lower cardiovascular death over 3.6 years of daily use — not occasional.
Naturally caffeinated (~12 mg per serving, about a quarter of a cup of coffee).
Most cacao supplements deliver 5 to 10 percent of the dose the cardiovascular trials actually used. We built CCV-3® to close that gap.
Cardiovascular benefit from cacao is dose-dependent. Below 200 mg of flavanols a day, RCTs show no significant change in flow-mediated dilation, blood pressure, or downstream cardiovascular outcomes. The shelf almost never goes higher than that.
Cacao flavanols stimulate endothelial nitric oxide synthase, the enzyme that keeps arteries supple. Schroeter et al. isolated (–)-epicatechin as the active monomer responsible for cocoa's vascular effects. CCV-3® delivers 600 mg of standardized epicatechin per scoop.
The COSMOS trial randomized adults to daily cocoa flavanols for 3.6 years. The pre-specified secondary endpoint, cardiovascular mortality, fell 27%. This is the only trial of its size on this nutrient class.
Each pillar is a measured outcome from peer-reviewed cacao flavanol research.
Cacao flavanols promote vasodilation by supporting nitric oxide synthesis — the foundational pathway endothelial cells use to regulate vascular tone.
Heiss et al · J Cardiovasc Pharmacol · 2010Improved cerebral blood flow correlates with measurable gains in working memory and processing speed across multiple controlled trials.
Brickman et al · Nat Neurosci · 2014Daily flavanol intake at studied doses improves flow-mediated dilation — the gold-standard measure of vascular health.
Schroeter et al · PNAS · 2006Naturally occurring 12mg of caffeine and theobromine deliver clean morning lift — no jitters, no afternoon crash, no synthetic stimulants.
Cacao flavanols rank among the highest natural antioxidants by ORAC score, neutralizing oxidative stress in vascular tissue.
Vinson et al · J Agric Food Chem · 2006The COSMOS trial measured a 27% reduction in cardiovascular death over 3.6 years — the strongest cacao nutrition outcome ever published.
COSMOS Trial · Am J Clin Nutr · 2022Cacao flavanols are one of the most studied cardiovascular nutrients in the published literature.
"Daily cacao flavanol supplementation reduced cardiovascular death by 27% over 3.6 years in a large generally-healthy adult population."
"Epicatechin from cacao improved flow-mediated dilation by 14% in healthy adults — the gold-standard measure of vascular function."
"High-flavanol cacao intake reversed dentate gyrus age-related decline by an estimated 11 years on neurocognitive testing."
No marketing fluff, just numbers. Compare like for like.
If it does not earn a place on the label, it does not make it into the jar.
A single source. A single dose. A single way to make it.
Morning is best. Flavanols pair with daily routines. Take it the same way every day for the cumulative cardiovascular benefit COSMOS measured over 3.6 years.
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