Circulation & Recovery · CCV-3®

The cacao dose for vasodilation, vascular endurance, and recovery.

1,200 mg of cacao flavanols. Promotes endothelial nitric oxide synthase activity. The studied dose for sustained circulation, vascular endurance under load, and faster between-session recovery.

Begin the circulation ritual

Schroeter et al · PNAS 2006 · COSMOS · Am J Clin Nutr 2022

The cacao dose for <em>vasodilation, vascular endurance, and recovery.</em>
The cacao dose for <em>vasodilation, vascular endurance, and recovery.</em>
The cacao dose for <em>vasodilation, vascular endurance, and recovery.</em>
Circulation & recovery · CCV-3®

The studied dose, cleared for sport.

1,200 mg of cacao flavanols. Promotes endothelial nitric oxide synthase activity for vasodilation, vascular endurance, and faster between-session recovery.

4.9 1,247 verified reviews 21,442-person trial
Nitric oxide support Vascular endurance 1,200 mg cacao flavanols / scoop
Free shipping over $50 Cancel anytime Free shipping on subscriptions

One scoop. 60–90 minutes pre-workout. Or morning ritual for daily vascular health.

The studied dose linked to a 14% increase in flow-mediated dilation (Schroeter PNAS 2006). Built to the COSMOS dose. Same SKU as Heart Health and Menopause, framed for movement.

What's inside
  • 1,200 mg cacao flavanols — standardized to 600 mg (−)-epicatechin per scoop
  • Cacao Powder — cold-pressed, low-heat processed
  • Cacao Butter — cold-pressed, flavanols intact
  • Vanilla Bean — whole bean, sun-cured
  • Lucuma Powder — low-glycemic, no added sugar
  • Mineral Pink Salt — unrefined

Other ingredients: none. No fillers. No proprietary blends. No preservatives.

How to use it

One scoop. Eight ounces of warm oat milk or hot water.

Best timing for performance: 60–90 minutes pre-workout. Plasma nitric-oxide markers peak in that window. For daily vascular health, morning with breakfast works equally well — outcomes accumulate with consistency.

Naturally caffeinated (~12 mg per serving, about a quarter of a cup of coffee).

The published record
  • Schroeter et al. PNAS 2006 — 14% increase in flow-mediated dilation (vasodilation) from a 900-mg cacao flavanol dose
  • Heiss et al. Circulation 2010 — endothelial NO-synthase upregulation, sustained vasodilation
  • Sansone et al. Br J Nutr 2015 — cacao flavanols improve vascular function in healthy adults
  • COSMOS Trial · 21,442 adults · Am J Clin Nutr 2022 — 27% lower cardiovascular death at 1,200 mg flavanol dose
The program
  • Subscribe & Save 20% off retail — locked at $31.98 vs $39.99
  • Free shipping on every subscription order
  • Cancel anytime — 30-day, 60-day, or 90-day cadence
  • 90-day quality guarantee — full refund, no questions
  • One use per customer on the WELCOME10 code, stackable with subscribe
Why athletes are paying attention

Vasodilation under load is a trainable variable.

The athletes who switched to cacao flavanols didn't do it for marketing. They did it because the dose hit a measurable ceiling on flow-mediated dilation that their pre-workouts couldn't.

01
The Problem

Most pre-workouts boost output, not vasculature.

Caffeine, citrulline, beta-alanine: each pushes a different lever, but none directly upregulate endothelial nitric oxide synthase (eNOS). That's why pre-workouts plateau on circulation while still delivering acute energy. The cap is vascular, not muscular.

Bryan & Lefer · Heart Fail Rev · 2009
02
The Mechanism

Epicatechin upregulates eNOS directly.

Schroeter isolated (–)-epicatechin as the cocoa monomer that raises eNOS activity and produces measurable 14% increase in flow-mediated dilation in healthy adults. CCV-3® delivers 600 mg of standardized epicatechin per scoop, taken 60 to 90 minutes before training.

Schroeter et al · PNAS · 2006 · 14% FMD increase
03
The Outcome

Built for movement. The COSMOS dose, every scoop.

CCV-3® delivers the studied dose, in one daily ritual. The mechanism and the dose line up with what the trials measured. Same SKU as the Heart and Menopause rituals. Framed for movement.

COSMOS · Am J Clin Nutr 2022 · Schroeter et al · PNAS 2006
Vascular & circulation outcomes

What the research measured.

14%
Increase in flow-mediated dilation
Schroeter et al · PNAS 2006
27%
Lower cardiovascular death
COSMOS · Am J Clin Nutr 2022 · 21,442 adults · 3.6 years
1,200 mg
Cacao flavanols per scoop
Studied dose · matches every cited RCT
Studied mechanism

Six pillars of cardiovascular vitality.

Each pillar is a measured outcome from peer-reviewed cacao flavanol research.

Healthy Blood Flow

Cacao flavanols promote vasodilation by supporting nitric oxide synthesis — the foundational pathway endothelial cells use to regulate vascular tone.

Heiss et al · J Cardiovasc Pharmacol · 2010

Cognitive Sharpness

Improved cerebral blood flow correlates with measurable gains in working memory and processing speed across multiple controlled trials.

Brickman et al · Nat Neurosci · 2014

Endothelial Function

Daily flavanol intake at studied doses improves flow-mediated dilation — the gold-standard measure of vascular health.

Schroeter et al · PNAS · 2006

Sustained Energy

Naturally occurring 12mg of caffeine and theobromine deliver clean morning lift — no jitters, no afternoon crash, no synthetic stimulants.

Antioxidant Defense

Cacao flavanols rank among the highest natural antioxidants by ORAC score, neutralizing oxidative stress in vascular tissue.

Vinson et al · J Agric Food Chem · 2006

27% Lower CV Death

The COSMOS trial measured a 27% reduction in cardiovascular death over 3.6 years — the strongest cacao nutrition outcome ever published.

COSMOS Trial · Am J Clin Nutr · 2022

Peer-reviewed evidence.

Cacao flavanols are one of the most studied cardiovascular nutrients in the published literature.

Am J Clin Nutr2022
Randomized controlled trial

"Daily cacao flavanol supplementation reduced cardiovascular death by 27% over 3.6 years in a large generally-healthy adult population."

Sesso, H.D. et al.

Journal:Am J Clin NutrYear:2022N:21,442
PNAS2006
Mechanism study

"Epicatechin from cacao improved flow-mediated dilation by 14% in healthy adults — the gold-standard measure of vascular function."

Schroeter, H. et al.

Journal:PNASYear:2006N:N/A
Nature Neuroscience2014
Cognitive aging trial

"High-flavanol cacao intake reversed dentate gyrus age-related decline by an estimated 11 years on neurocognitive testing."

Brickman, A.M. et al.

Journal:Nature NeuroscienceYear:2014N:37
Why Harmony

The honest comparison.

No marketing fluff, just numbers. Compare like for like.

Spec
Harmony
Typical cacao powder
Flavanol capsule
Cacao flavanols
1,200 mg
~80 mg
~150 mg
Standardized epicatechin
✓ 600 mg
Not listed
~40 mg
Extraction
Cold-pressed, low heat
Alkali Dutched
Solvent extracted
Ingredients
✓ 5 whole foods
Rare
Sometimes
Caffeine per serving
~12 mg
~25 mg
0 mg
Ingredients
5
1 to 3
10+

Five ingredients. Nothing else.

If it does not earn a place on the label, it does not make it into the jar.

01
Cacao Powder
Cold-pressed, low-heat processed.
02
Cacao Butter
Cold-pressed, flavanols intact.
03
Vanilla Bean
Whole vanilla bean, sun-cured.
04
Lucuma Powder
Low-glycemic, no added sugar.
05
Mineral Pink Salt
Unrefined, untreated.

Built to one standard. Every batch.

A single source. A single dose. A single way to make it.

Premium cacao
Cold-pressed cacao Low-heat processed Non-alkalized
Cold-pressed in small batches to preserve flavanol structure.
Cold-press extraction
Method: Cold-press, low heat No solvents No alkalization
Heat-sensitive flavanols are preserved when cacao is processed gently.
Five-ingredient formula
Cacao · Cacao butter Vanilla · Lucuma Mineral salt
The label is the recipe — no fillers, no proprietary blends, no preservatives.
Harmony morning ritual
The Ritual

One scoop. Hot water or oat milk.

Morning is best. Flavanols pair with daily routines. Take it the same way every day for the cumulative cardiovascular benefit COSMOS measured over 3.6 years.

01
Scoop
02
Stir
03
Sip

Real circulation customers.

4.9 out of 5
Based on 1,247 customer reviews
Marcus T.
Marcus T.
Real buyer
March 2026
Vasodilation under load is real
Cyclist, 200km/wk on the bike. Took Harmony 60 min before rides for four weeks. Sustained heart rate is steadier and recovery between sets is noticeably faster.
Real Buyer
Coach Jake
Coach Jake
Real buyer
February 2026
The studied dose, every scoop
I work with serious athletes. The studied dose is non-negotiable. Harmony's the only cacao flavanol product I've found that hits the COSMOS dose in one scoop.
Real Buyer
Reema A.
Reema A.
Real buyer
January 2026
Pump and hand warmth at the gym
Notice the pump on chest and back days. Hands stay warm even on cold mornings. The dose really does shift circulation, felt it within a week.
Real Buyer
Daniel H.
Daniel H.
Real buyer
December 2025
Replaced the pre-workout
Had been on a $50/mo pre-workout. Switched to Harmony. Cleaner energy, no jitters, vasodilation actually shows up in the mirror. Will not go back.
Real Buyer
Asha P.
Asha P.
Real buyer
November 2025
Recovery is the difference
44 and lifting heavy three days a week. Recovery between sessions used to take 36 hours. After five weeks on Harmony it's closer to 24. Numbers go up, soreness goes down.
Real Buyer
Coach Marcus
Coach Marcus
Real buyer
October 2025
I tried every cacao extract
I've explored cacao extracts for years across athletes. Harmony completely solves the dosing problem. 1,200mg in one scoop, clean, no fillers.
Real Buyer
REAL CIRCULATION CUSTOMERS

Real customers. Real recovery.

Vertical reviews from Instagram, TikTok, and Facebook. Tap any card to play with sound.

TikTok
@coach.marcus
I tried every cacao extract. Harmony solves the dosing problem.
Instagram
@biohacker.daily
30 days in. Sharper, calmer, no afternoon crash. Pump is real.
@reema.lifts
Hand warmth, pump, vasodilation. Felt it in a week.
Instagram
@daniel.cleanfuel
Replaced my $50 pre-workout. Cleaner energy, real vasodilation.
TikTok
@asha.heavy
Recovery 36hrs to 24hrs. Five weeks. The dose is the difference.

Frequently asked questions.

01 What is Harmony MD Cacao Cellular Complex?
A cacao powder developed with physician input, delivering 1,200mg of flavanols per scoop — the studied dose from the COSMOS trial published in the American Journal of Clinical Nutrition.
02 How long until I notice results?
Most users notice changes within 7–14 days. The COSMOS trial measured outcomes across 3.6 years of daily use, so the cumulative effect builds with consistent use.
03 Is it allergen-free?
Yes. The formula is vegan, non-GMO, gluten-free, soy-free, and contains no artificial sweeteners, fillers, or preservatives. Five ingredients only.
04 What is CCV-3® and why does it matter?
CCV-3® is our internal quality standard ensuring each batch delivers exactly 1,200mg of cacao flavanols with 600mg standardized epicatechin — built around the same flavanol and epicatechin mechanism studied in COSMOS, at 2.4× the trial flavanol dose. Without standardization, you can't reproduce the mechanism reliably.
05 How is each batch verified?
Every batch is standardized to the CCV-3® protocol — 1,200 mg of cacao flavanols and 600 mg of (−)-epicatechin per scoop. Verified to spec before it ships.
06 How do I manage my subscription?
Log in to your account portal to pause, skip, change frequency, or cancel at any time. No minimums. No penalties.
07 How long does one jar last?
Each jar contains 30 servings at the studied 10g daily scoop — one full month of the morning ritual at the COSMOS dose. Subscribers receive a fresh jar every 30 days so their supply never lapses.
08 Can I take Harmony with other medications?
Always consult your physician before adding any supplement to your regimen, particularly if you take blood thinners, statins, or blood pressure medication. The COSMOS trial included participants on various medications; your clinician knows your case.
09 Does Harmony have any caffeine?
Each serving contains approximately 12mg of naturally occurring caffeine — less than a quarter of a standard cup of coffee. This is naturally present in cacao and cannot be removed without destroying the flavanols.
CCV-3® Standard 1,200 mg Standardized Flavanols Standardized cacao flavanol complex Standardized to spec 1,200 mg cacao flavanols / scoop Vegan · Non-GMO Subscribe & Save 20% CCV-3® Standard 1,200 mg Standardized Flavanols Standardized cacao flavanol complex Standardized to spec 1,200 mg cacao flavanols / scoop Vegan · Non-GMO Subscribe & Save 20%
1,200mg flavanols
600mg epicatechin
Cold-pressed
Premium cacao
Five whole-food ingredients
Subscribe & Save
Begin the ritual

Start the circulation ritual today.

Subscribe and receive a fresh jar every 30 days. Pause, skip, or cancel anytime from your account.

Free shipping over $50 Cancel anytime Third-party tested